What is KSM-66 Ashwagandha?

The gold standard of ashwagandha extracts. Here's what the research actually shows.

KSM-66 is a patented, full-spectrum ashwagandha root extract manufactured by Ixoreal Biomed. It is standardized to contain a minimum of 5% withanolides and is the most clinically studied ashwagandha extract available, backed by over 50 published clinical trials.

KSM-66 at a Glance

  • Manufacturer

    Ixoreal Biomed (India)

  • Plant Part

    Root only

  • Standardization

    5% withanolides

  • Clinical Studies

    50+ trials

How Does KSM-66 Reduce Stress?

Your stress response works like this:

1. Brain perceives stress → signals hypothalamus
2. Hypothalamus → signals pituitary gland
3. Pituitary → signals adrenal glands
4. Adrenals release cortisol

Chronic stress = constantly elevated cortisol.
Elevated cortisol = brain fog, poor sleep, burnout.

KSM-66 helps modulate this cycle at the hormonal level.

KSM-66 also supports GABA activity, serotonin pathways, and healthy inflammatory response.*

KSM-66 also influences

  • Serotonin pathway

    May support mood balance

  • GABA receptors

    Mimics calming neurotransmitter activity

  • Oxidative stress

    Antioxidant properties

  • Inflammation

    Helps regulate inflammatory response

What Does the Research Show?

  • Study design

    64 subjects • Double-blind • Placebo-controlled

  • CORTISOL REDUCTION

    27.9% vs placebo (p=0.0006)

  • DOSE USED

    600mg/day for 60 days

  • STRESS SCORES

    Significant reduction (p<0.0001)